Crucially, NHS prescribing of GLP-1 medications is subject to strict eligibility criteria and typically requires specialist initiation or shared care arrangements
1041 Derivation of a preference-based value set for the Short Warwick-Edinburgh Mental Well-being Scale (SWEMWBS) to allow calculation of Mental Well-being Adjusted Life Years (MWALYs) Hei Hang Edmund Yiu 1 , Stavros Petrou 2 , Sarah Stewart-Brown 3 , David Churchman 4 , Jason Madan 3 1 Department of Pharmacology and Pharmacy LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong, 2 Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK, 3 Warwick Medical School, University of Warwick, Warwick, UK, 4 InSpired Health Outcomes, Witne, UK Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :1041 Aims Concerns have been raised about the sensitivity of widely used preference-based instruments, such as the EQ-5D, in valuing mental health benefits
However, due to the low predictive value, the high number of false positive results may create a high subsequent testing burden
GLP-1 Receptor Activity Like semaglutide, retatrutide activates GLP-1 receptors to reduce hunger and increase satiety
Rybelsus has been a powerful tool, but not an easy one