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Therapy with DPP4is proved neutral, not superior, in terms of major adverse cardiac events, including stroke, in previous DPP4i cardiovascular outcome trials in patients with T2DM 79,80

doi: 10.1016/j.metabol.2016.03.009 47 LibermanAEsserMMarxNBurgmaierM

Many patients did not stick with the treatment, and there was a small but notable increase in risk for acute pancreatitis

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