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2 The APA article notes that many patients discontinue treatment within a year because of side effects, cost, access issues, or other challenges, but this source does not establish mental distress as a uniform or primary reason across all patients

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Diabetes 48:22702276 Duality of interest The author declares that there is no duality of interest associated with this manuscript

This screening is essential because GLP-1 medications affect appetite signaling and glucose metabolism system-wide, and individual tolerability varies significantly based on metabolic state and underlying conditions