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The increment in intestinal permeability is another prominent mechanism in the gut-brain axis communication in patients with migraine, leading to inflammation and the release of pro-inflammatory cytokines (200, 201)

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The GLP-1 medicines semaglutide and tirzepatide do not alter disease-related pathology, behaviour or cognitive function in 5XFAD and APP/PS1 mice

Liu Zhaozhao (90) reported that liraglutide can activate GLP-1Rs, and that liraglutide can promote the proliferation of breast cancer cells by activating GLP-1Rs

Because several donor atoms participate simultaneously, the complex is generally more stable than one formed by a single ligand interaction