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Tri-color staining showed that collagen (blue) began to form in the junctional area on the third day after injury

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FIGURE 4 5.1.3 Regulation of autophagy in mammalian cells Multiple kinases are responsible for regulation of mammalian autophagy, among them, the mechanistic target of rapamycin (mTOR) and adenosine monophosphate (AMP)-activated protein kinase (AMPK) play important and antagonistic roles (Tamargo-Gmez and Mario, 2018)

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Sotyktu, a small molecule TYK2 inhibitor, was the first oral drug to open the psoriasis market

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