central and peripheral glp 1 systems independently suppress eating Mechanisms of GLP-1 Receptor Agonist-Induced Weight Loss: A Review of Pathways in Appetite and Energy Regulation Effects of GLP-1 on appetite

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In addition, GLP-1RAs act as a key determinant of blood glucose homeostasis due to their abilities to slow gastric emptying, to enhance pancreatic insulin secretion, and suppress pancreatic glucagon secretion [5]