By binding to ER in endothelial cells, estrogens induce nitric oxide (NO) release, consequently producing vasodilation (Penotti et al., 1996), and the impedance of this flow appears to be reduced after starting hormone (estrogen) replacement therapy (HRT) ( Estrogens and Neurodegenerative Diseases Experimental and clinical data suggest that estrogens have protective effects against neurodegenerative diseases (Kumar et al., 2010
They slow gastric emptying, increase satiety, and reduce appetite signaling in the brain
If you have any persistent side effects, you should contact your healthcare provider for further advice, as you may need to stop treatment
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