The role of glutathione in copper metabolism and toxicity
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Cohen LH, Vamos E, Heinrichs C, Toppet M, Courtens W, Kumps A, Mardens Y, Carlsson B, Grillner L, Larsson A: Growth failure, encephalopathy, and endocrine dysfunctions in two siblings, one with 5-oxoprolinase deficiency
A dose-escalation study conducted at the University of North Carolina's Nutrition Research Institute found that hepatic phosphatidylcholine synthesis increased linearly with methionine intake up to approximately 4050mg per injection, then plateaued
Only the naturally occurring R isomer is bound to protein and acts as an essential cofactor in biological systems (Reed, 1998)