insulin resistance and glp-1

insulin resistance and glp-1 Receptor Agonists as Treatments for Type 2 Diabetes The Role of Glp-1 Receptor

Name: insulin resistance and glp-1 Receptor Agonists as Treatments for Type 2 Diabetes The Role of Glp-1 Receptor
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Graphical Abstract Access this article Similar content being viewed by others Data availability All the data in this paper are correct

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doi: 10.1016/j.cimid.2011.01.004 3 LeBlancSJ

The molecule makes three changes to the native hormone fragment: a lactam bridge between the aspartate side-chain carboxyl at position 5 and the lysine side-chain amine at position 10, inversion to D-phenylalanine at position 7, and substitution of norleucine for the oxidation-prone methionine at position 4