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MPO ( R = 0.566, p = 0.044) and MMP-9 ( R = 0.441, p = 0.05) were negatively correlated and TIMP-1 ( R = 0.367, p = 0.089) was marginally positively correlated with duration of PTSD illness (see Figure 3)

However, while a great deal of literature exists demonstrating upstream loss or activation of NRF2 can have significant consequences, very few studies have linked NRF2 with the actual downstream targets and signaling cascades that dictate its regulation of stem cell survival

Together, they help neutralize free radicals, reduce oxidative stress, support melanin regulation, and promote cellular detoxification

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