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doi: 10.1038/ncomms13419 71 PiccaARiezzoGLezzaAMSClementeCPesceVOrlandoAet al
+2+8 C,
Cancer suppression: Experiments have found that MOTS-c can suppress certain types of cancer cell growth by acting through several signalling pathways [18]
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Initially, NOX2 activation generates significant quantities of H 2 O 2 /O, which subsequently activate key signaling pathways such as MAPK and JNK, leading to nuclear membrane breakdown and chromatin decondensation, culminating in NET formation
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