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CYP7A1 is the rate-limiting enzyme in converting cholesterol to bile acids, and LXRs, which function as cholesterol sensors, increase Cyp7a1 expression in response to acute cholesterol intake in mice [2,33]

Full text: Kumar, P., Osahon, O., Vides, D

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Therefore, since diet is a source of exogenous oligo-elements and vitamins, current clinical practice suggests to integrate the diet with some nutritional supplements that are capable to reverse this imbalance, inducing the control of the OS and improving fertility (49)