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Iba1 and GFAP staining Sections were deparrafinised and rehydrated as above and subjected to antigen retrieval at pH 9 using Access super RTU (Menarini) for 30 min at 125 C with 20 psi

On the basis of the identification of new causative pathways, the subphenotyping of asthma across the lifecourse of patients is paving the way for more-personalized and precise pathway-specific approaches for the prevention and treatment of asthma, creating the real possibility of total prevention and cure for this chronic inflammatory disease

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Pfizer discussed the case with the study site and internal and external hepatologists, as well as shared clinical details with regulators, including the FDA. The pharma company did not provide any additional details of the discussions with regulators