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When medication is indicated, NICE recommends : Methylphenidate (e.g., Ritalin, Concerta XL) or lisdexamfetamine (Elvanse) as first-line pharmacological treatments Atomoxetine (Strattera) a non-stimulant selective noradrenaline reuptake inhibitor when stimulants are not suitable or have been ineffective Guanfacine (Intuniv) a non-stimulant alpha-2 adrenergic agonist licensed for children and young people aged 6-17 years (not licensed for adults in the UK) These medications have undergone rigorous clinical trials demonstrating efficacy and safety in ADHD populations, with well-established monitoring protocols to manage potential adverse effects

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They need to establish that the risk was known or reasonably knowable, that it was material to a patient's decision to take the drug, and that the label failed to disclose it adequately

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doi: 10.3171/2022.9.JNS221565 296 Risby-JonesG.MarallagJ.JagarajC