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Mara Gordon is a family physician in Camden, N.J., and a contributor to NPR

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By affecting these hormones, Semaglutide helps to slow down the emptying of your stomach and lower blood sugar levels, effectively helping you to feel fuller for longer and reducing your appetite for sustained weight loss

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The maintenance study FIGARO UC 303 (NCT03290781) enrolled 366 responders who continued their induction dose or switched to placebo for 52 weeks, demonstrating that both 25mg and 75mg doses significantly outperformed placebo with clinical remission rates of 53.5% and 40.2% respectively versus approximately 8-13% placebo, while inclusion criteria required patients aged 1866 years with moderate to severe disease and the completed studies showed favorable safety profiles with most common adverse events being UC worsening, arthralgia, and nasopharyngitis (51)

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