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Tirichen H, Yaigoub H, Xu W et al (2021) Mitochondrial reactive oxygen species and their contribution in chronic kidney disease progression through oxidative stress

Hypotension/Bradycardia Advise patients who have a history of syncope or may have a condition that predisposes them to syncope, such as hypotension, orthostatic hypotension, bradycardia, or dehydration, to avoid becoming dehydrated or overheated [see Warnings and Precautions (5.1)]