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These studies support the clinical value of measuring both reduced and oxidized glutathione, and using the GSH:GSSG ratio as a sensitive biomarker of oxidative stress, detox capacity, and biological aging

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First-trimester exposure and major malformations similarly showed no significant association, a result confirmed in a sensitivity analysis restricted to adjusted estimates

One limitation of the current literature is the lack of extensive clinical studies exploring the direct neuroprotective effects of GLP-1RAs in human populations