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MEL has also been shown to alleviate MS stress-induced insulin resistance and that it sensitizes cells to apoptosis by inhibiting COX expression, increasing the Bax/Bcl-2 ratio and chemotherapy regimen (CHOP) (231)

Neurochem Int 55(13):106112

Moreover, tirzepatide can lead to a mean reduction in body weight, as both GIP and GLP-1 play roles in modulating appetite and satiety [20]

It does this by activating GLP-1 receptors in the brain and digestive system

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