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In most cells, cysteine is obtained through the system xc- antiporter, which exchanges extracellular cystine with intracellular glutamate [23]

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By doing so, catalase acts as a defense mechanism, deterring the buildup of H 2 O 2 which, if left unchecked, could result in the creation of the immensely reactive hydroxyl radicals ( OH), especially under the conditions of CLD [45,46]

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Nutritional such as inadequate dietary intake of vitamin B12 (e.g., strict vegan diet) and malnutrition