Klonoff, MD, medical director of the Diabetes Research Institute at Mills-Peninsula Medical Center in San Mateo, California, noted that the findings of the Hathaway study, based on a single tertiary care university eye clinic, might not pertain to the general population. To assess the risk of NAION in patients prescribed semaglutide for diabetes or obesity, he performed a series of real-world analyses based on the electronic health record and claim dataset of Atropos Health, comprising 66 million people nationally
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In the final regression model, age [adjusted OR = 1.05 (1.041.07)], gender [adjusted OR = 2.32 (1.423.80)], number of combined oral drugs [adjusted OR = 1.84 (1.622.10)], and history of gastrointestinal disorders [adjusted OR = 6.22 (3.4911.11)] were associated with GISEs caused by GLP-1RAs
Lee BJ, Lin JS, Lin YC, Lin PT (2015) Anti-inflammatory effects of L-carnitine supplementation (1000 mg/d) in coronary artery disease patients
In my experience, theres a reason patients increase their doses as recommended: they simply dont lose enough weight on the starting doses