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The advantages of GLP-1 agonists include substantial clinical trial data supporting their efficacy and safety, FDA approval for weight management in certain populations, proven results with many users losing 15-20% or more of body weight, and effects on appetite that make caloric restriction feel natural

However, under therapy-induced stress, cancer cells and non-neoplastic stromal cells mobilize survival signals that nurture the residual disease until minority drug-resistant clones emerge to lead the outgrowth of a drug-resistant tumor

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However, knowing what to watch for can help you catch any issues early and adjust your routine accordingly

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