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Quercetin ameliorates cognitive impairment in depression by targeting HSP90 to inhibit NLRP3 inflammasome activation

However, a meta-analysis of randomized controlled trials found that NAC was not significantly better than placebo in treating severe depression or bipolar disorder ( Overall, NAC exhibits multiple biological activities, demonstrating promise as a treatment for SZ, MDD, and AN

This is because methylation is responsible for helping to clear this inflammatory amino acid out of the body