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The first medication in this class, sitagliptin, received FDA approval in 2006 for the treatment of type 2 diabetes

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Neuron 21(4):695705 Li Y, Wu H, Khardori R, Song Y-H, Lu YW, Geng Y-J (2009) Insulin-like growth factor-1 receptor activation prevents high glucose-induced mitochondrial dysfunction, cytochrome-c release and apoptosis

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