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doi:10.1007/s00109-016-1488-y

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Increased serum matrix metalloproteinase-9 (MMP-9) levels in young patients during bipolar depression

That means treatment is not simply about receiving a prescription

This enzyme is localized into mitochondria and acts in two crucial pathways of the energetic metabolism, such as the Krebs cycle and the electron transport chain, by converting succinate into fumarate, together with the reduction of flavin adenine dinucleotide (FAD) into FADH 2