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Astaxanthin bioactivity is determined by stereoisomer composition and extraction method

Ethics declarations Conflicts of interest Juan Manuel Perics has received research support from Siemens, Boehringer-Ingelheim, Madrigal and NovoNordisk outside the submitted work

Metabolic reprogramming of pulmonary artery smooth muscle cells, pulmonary artery endothelial cells, and others provides the energy and material basis for abnormal proliferation of vascular cells

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This is simply the inverse of a strategy used by some large DNA viruses to maximize DNA production, by encoding their own thioredoxin-like proteins, glutaredoxins and even entire RNR genes ( both of the essential redox systems required to sustain DNA synthesis, and thereby conserve ribonucleotides to enhance RNA synthesis for virus production