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Biol Psychiatry 54 : 418426

Patients with obesity have altered gut microbiome, as food and fiber intake can be a driver of natural selection in the gut microbiome

CJC-1295 (No DAC) is a synthetic analogue of Growth Hormone Releasing Hormone (GHRH 1-29), designed to stimulate the pituitarys natural growth hormone secretion through transient receptor activation

Searching for a structural endophenotype in psychosis using computational morphometry

To date, incretin-based approaches for obesity management appear as the most promising and rapidly developing (Supplementary Table 1), with innovations such as once-weekly (OW) injectable triple GIPR/GCGR/GLP-1R agonist retatrutide (LY3437943), cagrilintide (long-acting amylin analogue)/semaglutide 2.4 mg (CagriSema) combination, GCGR/GLP-1R dual agonists, high-dose oral semaglutide, and oral non-peptide GLP-1 receptor agonist orforglipron, with relevant implications in terms of patients compliance and environmental sustainability