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Rapid infusion rates can trigger nausea, flushing, and discomfortcomplications that require immediate medical adjustment

For intra-articular applications, we typically prefer leukocyte-poor PRP to minimize post-injection flare, while leukocyte-rich PRP may be considered for some tendinopathies where a stronger inflammatory reset is useful

The short answer: the ideal needle size for a B12 injection depends on the injection method