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Based on domain architecture comparison with HNF4 58,59 , we engineered an NHR-49 truncation (295422) to disrupt ligand binding by removing a majority of the ligand binding domain, while retaining its analogous N-terminal, DNA-binding, hinge, and C-terminal domains (Fig

PMID: 97 SafaeiZBakhshalizadehSEsfahaniMHNSeneAANajafzadehVSoleimaniMet al

Without this information, values from different studies may not be directly comparable

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