glutathione congestive heart failure Abbreviations CHF: failure; CRP: C-reactive protein; Glutathione Infusion Before and 3

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343 Reduced astrocytic homoeostatic support is also evidenced by the loss of endfeet polarisation of AQP4 344 and decreased expression of monocarboxylate transporter 1 345 responsive for lactate supply of neurones

2 (download XLSX Numerical data for titration experiments Source Data Fig

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A subsequent larger RCT (n=72) confirmed these findings, showing improvements in gait speed, grip strength, exercise capacity, waist circumference, and systolic blood pressure (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]