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According to the latest update of the International Diabetes Federation (2025) report, the numbers continue to increase
The use of the drugs has increased substantially in recent years (e.g., Lee, et al., 2024
2,20 Antifibrotic Effects GLP-1RAs downregulate transforming growth factor- signalling pathways in myocardial fibrosis
Diabetes Obes Metab 25:18131822 Palmer SC, Tendal B, Mustafa RA, Vandvik PO, Li S, Hao Q, Tunnicliffe D, Ruospo M, Natale P, Saglimbene V, Nicolucci A, Johnson DW, Tonelli M, Rossi MC, Badve SV, Cho Y, Nadeau-Fredette AC, Burke M, Faruque LI, Lloyd A, Ahmad N, Liu Y, Tiv S, Millard T, Gagliardi L, Kolanu N, Barmanray RD, McMorrow R, Raygoza Cortez AK, White H, Chen X, Zhou X, Liu J, Rodriguez AF, Gonzalez-Colmenero AD, Wang Y, Li L, Sutanto S, Solis RC, Diaz Gonzalez-Colmenero F, Rodriguez-Gutierrez R, Walsh M, Guyatt G, Strippoli GFM (2021) Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials