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Lyophilized powder maintains stability for 2-3 years at freezer temperatures (-20C to -80C) or 1-2 years refrigerated at 2-8C

"We already do this with drugs like tamoxifen, which healthy high-risk women take to lower their odds, so a preventive medication isn't a new idea," he says

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But in practice, these are fundamentally different compounds with different receptor profiles, different side effect landscapes, and different outcomes for the people who use them

Users who escalate from 2.5mg of tirzepatide to 5mg and beyond sometimes notice that reactions worsen at each new dose level before stabilizing