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The dosage of metformin varies depending on the formulation: 1

10.1371/journal.pone.0050683 PLoS One 125 LouwiesT.JohnsonA

Sulfonylureas like glimepiride were once a first-line diabetes treatment, but their popularity has declined because they carry risks of weight gain and dangerous blood sugar drops

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(4) The phylum Actinobacteria includes numerous beneficial gut bacteria, such as Bifidobacterium and Collinsella , which modulate the immune system, improve gut barrier function, and reduce inflammation ( 3.3 Gut microbiota metabolites Gut microbiota-dependent metabolites act as a bridge that connects the dynamic equilibrium between the host and the gut microbiota (Schoeler et al., 2019)