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In summary, artesunate inhibits the activation of M1 macrophages and the RIPK1/RIPK3/MLKL signaling cascade by down-regulating Mincle expression, consequently reducing both the inflammatory response and necroptosis, thereby ameliorating renal injury in AKI

The drinks contain 15 grams, 20 grams and 30 grams of protein per serving, respectively

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S2A), it can mediate this translocation when co-expressed with G1*arrestin3 (Additional file 1: Fig