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These enzymes can assemble into a functional complex on the peroxisomal membrane, enhancing substrate conversion efficiency

And protein kinase A phosphorylates hormone-sensitive lipase, the enzyme that physically breaks triglycerides apart into free fatty acids and glycerol

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Yet, one study in 24 healthy volunteers reported no significant drug interactions with the co-administration of a single oral dose of lipoic acid (600 mg) and the oral anti-diabetic agents, glyburide (also called glybenclamide) or acarbose (Precose/Prandase/Glucobay) (119)