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Real-world patients may be older, present with multiple comorbidities, receive concomitant medications, and face challenges related to healthcare access, adherence, and long-term disease management

However, the TMZ in vivo treatment was also showed some improvement on CPT1B but with no significance, which was not consistent with the in vitro result (Figure 5F)

The antigens are associated to MHC II molecule that interacts with T-cell receptor of T CD4 + lymphocytes, leading the antigen recognition and, subsequently, activation

Peptides such as Thymosin Alpha-1 can modulate the immune system, making it more efficient at fighting off infections and diseases