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A clinical series published in the Journal of Clinical Medicine found that patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) who received intermittent intravenous saline infusions over a 9-week period showed beneficial effects in managing symptoms of dysautonomia and postural orthostatic tachycardia syndrome (POTS)

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The annulus fibrosus forms the outer ring, a complex series of fibrous layers made primarily of type I collagen arranged in alternating diagonal patterns

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