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The problem was the side effects associated, particularly with GLP-1, are what we call peak to trough: so the difference between the highest amount of drug and the lowest and then going back up again to the highest caused by this twice-a-day dosingwhich you can imagine someone bouncing around maybe two to three times, the drug at peak, then trough, causes a lot of GI distress

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Basic skincare recommendations (gentle cleansing, moisturizer, and sunscreen) after significant weight loss is not very different than before the weight loss

Results Clinical Characteristics and Treatment Results A total of 52 T2D patients treated with either liraglutide ( n = 22) or dulaglutide ( n = 30) were enrolled in this study from June, 2019 to Dec, 2020 ( Table 1 , Supplementary Figure 1 ), with 34 and 18 patients defined as responders and non-responders, respectively