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The loss of dopaminergic signaling also leads to increased glutamatergic activity, which may contribute to neuronal excitability and worsen symptoms

Vitamin C enhances collagen synthesis and helps regenerate glutathione, making it a valuable addition.

Stop and Smell the Rotten Eggs: How Hydrogen Sulfide Protects the Brain From Alzheimers Disease Despite being intricately involved in the creation of primordial life on Earth eons ago, hydrogen sulfide was previously thought to be solely a noxious environmental toxin that reeks of rotten eggs

Accordingly, neurodegenerative changes are present in other areas of the nervous system, such as the peripheral, autonomic, and enteric nervous systems [15, 16], and -synuclein aggregates may be detected outside the nervous system, including in the digestive tract, skeletal muscles, heart, adrenal glands, kidneys, urogenital system, and skin [22]

In clinical trials, l-arginine has been used safely with minor side effects for up to three months