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Seven additional Phase 3 readouts expected through 2026: TRIUMPH-1 (obesity), TRIUMPH-2 (obesity + diabetes), TRIUMPH-3 (obesity + cardiovascular risk), SELECT-M (MASH), SLEEP (OSA), BACK PAIN, and a cardiovascular/renal outcomes readout
Results develop over three to six months and last 18 to 24 months
Reason #3: Rapid weight loss can temporarily disrupt fertility When youre losing weight quicklyespecially 2+ pounds per weekyour hormones undergo significant shifts
For these reasons, species-specific and cell line-specific actions of TRPA1 channel activators such as JWU-A021 must be taken into account when planning high throughput screening approaches targeted at the identification of new GLP-1 secretagogues
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