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Inhibiting the glucose flux sensing modification O-GlcNAcylation increased the rates of mitophagy and ferritinophagy, both of which released a large amount of free iron and jointly induced ferroptosis [116]

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Receptor endocytosis, an intermediate step toward downregulation, is also necessary for resensitization via dephosphorylation and recycling 11, thus, totally inhibiting endocytosis will likely result in reduced signaling as surface receptors become desensitized via -arrestin recruitment

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Mutation spectrum in TPO gene of Bangladeshi patients with thyroid dyshormonogenesis and analysis of the effects of different mutations on the structural features and functions of TPO protein through in silico approach