Research done by Hayashi et al., 2023 showed that GLP-1s can affect thoughts as well as cravings and metabolism, and have been reported to quiet food noise, meaning that anecdotal reports from patients and clinicians alike point to a reduction in what has been colloquially termed food noise, as patients report experiencing less rumination and obsessive preoccupation about food. The same neuroplasticity benefits that psilocybin could offer for those recovering from addiction could also be applied to those looking to rewrite their brain patterns in relation to food
What makes them noteworthy is the novelty of their targets: Dihexa works through the hepatocyte growth factor (HGF) / c-Met receptor system, while PE-22-28 blocks TREK-1 two-pore domain potassium channels
Visible skin-related changes generally take 4 to 12 weeks and depend on formulation, dose, and lifestyle
21 The MAESTRO-NASH trial 2224 reported that steatohepatitis resolved without worsening of fibrosis in 25.9% of patients receiving resmetirom 80 mg and in 29.9% of those receiving 100 mg, compared with 9.7% in the placebo group, and fibrosis improved without worsening of steatohepatitis in 24.2% and 25.9%, respectively, compared with 14.2% with placebo
While it has basic medication tracking features, Dose AI shines most in nutrition guidance
