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In a landmark Phase 2 trial published in the New England Journal of Medicine, participants receiving the 12 mg dose experienced mean weight loss of 24.2% at 48 weeks, significantly exceeding results from earlier GLP-1 or dual-agonist therapies

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The ER thresholds and warning signs are the same regardless of diabetes status

Orna Fisher , a board-certified plastic surgeon with expertise in post-GLP-1 skin surgery, post-bariatric plastic surgery, and skin removal after weight loss

Lower doses mean less medication drawn per injection, which means each vial lasts longer in terms of dose count, but the BUD does not change