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The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia

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Discussion Colistin is a cyclic heptapeptide with an acylated tripeptide side chain that exerts its antimicrobial activity by disrupting the integrity of the bacterial membrane and increasing its permeability, leading to leakage of the cell content, membrane depolarization and cell death 1

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