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The sulfhydryl group on the cysteine residue, which is the reactive core of glutathiones antioxidant function, oxidises rapidly under gastric conditions

[16] After this initial phase, the frequency is reduced

At 48 weeks, participants on the 8 mg dose achieved a mean body weight reduction of 22.8%, while those on the highest 12 mg dose achieved a mean reduction of 24.2% compared to just 2.1% in the placebo group

Vitamin B12 is an essential nutrient required for the proper functioning of the body