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Notin C, Vallon L, Desbordes F, Leleu C

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MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells

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The meaningful comparison is at the three and six-month marks rather than week to week

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In animals, unlike the deletion of Slc7a11 , the deletion of the GGT family member Ggt1 results in increased GSH levels in urine, reduced cysteine levels in tissues and perinatal lethality 24

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