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Download the Shortform Chrome extension for your browser In this episode of the Huberman Lab podcast, psychologist Jamil Zaki examines the nature of cynicism - a pervasive mindset rooted in mistrust and the belief that others are motivated by self-interest
Jimnez-Loygorri JI, Villarejo-Zori B, Viedma-Poyatos , Zapata-Muoz J, Bentez-Fernndez R, Frutos-Lisn MD, et al
The SURMOUNT-1 trial, also published in the New England Journal of Medicine, found that participants lost an average of 16.0% of body weight at the 5mg dose, 21.4% at 10mg, and 22.5% at the highest 15mg dose over 72 weeks, compared to 2.4% in the placebo group with 89% to 96% of participants (depending on dose) reaching at least 5% weight loss
Safety Profile and Adverse Event Data Clinical trial safety data for retatrutide is broadly consistent with what has been reported for GLP-1 and GIP/GLP-1 classes, with a few nuances driven by the addition of glucagon receptor activity