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While our results are consistent with a senolytic effect of GPX4 inhibitors, the effects observed in some of the models, although significant, were modest, and we acknowledge that further investigation is needed to assess a potential translation to the clinic

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In exogenous research applications, the synthetic BPC-157 fragment has been evaluated across tissue types spanning the entire musculoskeletal system, gastrointestinal tract, liver, pancreas, cardiovascular system, and central nervous system producing consistently positive results across an unusually wide range of injury and dysfunction models

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