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Miao, S

Casey Dean, DO Board-Certified Family Medicine Physician Dr

Compounded GLP-1 therapy for weight loss are administered in weekly injections that are placed under the skin of the abdomen, thigh, or upper arm

GLP-1s Direct Biological Impact in the Brain Beyond their systemic metabolic effects, GLP-1 medications exert direct biological actions in the brain through widespread expression of incretin (GLP-1) receptors in regions critical for cognition, including the hippocampus, prefrontal cortex, and hypothalamus [14]

The article explains that semaglutide is a peptide hormone sensitive to heat and light, so refrigeration slows molecular degradation and preserves its ability to activate GLP-1 receptors