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Evid Based Complement Alternat Med 2013:639083

Like many providers who prescribe GLP-1s, Yuval Pinto, MD, has worked with select patients to gradually reduce how often they take the medication

Mu receptor occupancy results in K+ channel opening (hyperpolarization), Ca2+ channel closure ( glutamate, Sub P, CGRP), Na+ channel inhibition (hyperpolarization)

Such correlations provide a sound basis for generating testable hypotheses regarding causation

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