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However, enhancing the endogenous secretion of GLP-1 through dietary, microbial, or pharmacological stimuli represents a promising complementary strategy

Effect of antihypertensive treatment at different blood pressure levels in patients with diabetes mellitus: systematic review and meta-analyses

doi: 10.1016/j.jaad.2021.01.059 24

A small trial including 8 patients with T1D showed improved postprandial hyperglycemia despite 20% insulin dose reduction ( 5 Cardiovascular and renal outcomes with GLP-1RA in T1D In patients with T2D, large RCT studies have shown that GLP-1RA treatment reduces the risk of cardiovascular and renal outcomes ( 6 Practical issues when prescribing GLP-1RA in T1D GLP-1RA are not currently approved for treatment of T1D, but they may still be covered by insurance if prescribed to treat obesity in these patients (although insurance coverage for obesity remains limited)

Harrison, P., Kim, S